Prof. Dr. med. Daniela Grimm

Prof. Dr. med. Daniela Grimm
Professorin, Fachärztin für Innere Medizin und Klinische Pharmakologie
2022
Begutachteter Zeitschriftenartikel
Microgravity-related changes in bone density and treatment options - a systematic review
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 23 (2022), 15, insges. 23 S.
The cardiovascular system in space - focus on in vivo and in vitro studies
In: Biomedicines - Basel: MDPI, 2013, Bd. 10 (2022), 1, insges. 29 S.
Cancer studies under space conditions - finding answers abroad
In: Biomedicines - Basel: MDPI, 2013, Bd. 10 (2022), 1, insges. 28 S.
Three-dimensional growth of prostate cancer cells exposed to simulated microgravity
In: Frontiers in cell and developmental biology - Lausanne: Frontiers Media, 2013, Bd. 10 (2022), insges. 21 S.
Microgravity and Space Medicine 2.0
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 23 (2022), 8, insges. 6 S.
Recent advances in thyroid cancer research
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 23 (2022), 9, insges. 4 S.
The fight against cancer by microgravity - the multicellular spheroid as a metastasis model
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 23 (2022), 6, insges. 45 S.
Current knowledge about the new drug firibastat in arterial hypertension
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 23 (2022), 3, insges. 13 S.
What can biofabrication do for space and what can space do for biofabrication?
In: Trends in biotechnology - Amsterdam [u.a.]: Elsevier Science, 1983, Bd. 40 (2022), 4, S. 398-411
Sacubitril/valsartan, sodium-glucose cotransporter 2 inhibitors, and vericiguat for congestive heart failure therapy
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, 2004, Bd. 130 (2022), 4, S. 425-438
In prostate cancer cells cytokines are early responders to gravitational changes occurring in parabolic flights
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 23 (2022), 14, insges. 18 S.
Latest knowledge about changes in the proteome in microgravity
In: Expert review of proteomics - Abingdon: Taylor & Francis Group, Bd. 19 (2022), 1, S. 43-59
2021
Begutachteter Zeitschriftenartikel
The effect of continuous positive airway pressure therapy on obstructive sleep apnea-related hypertension
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 5, insges. 14 S.
Interaction network provides clues on the role of BCAR1 in cellular response to changes in gravity
In: Computation - Basel: MDPI, 2013, Bd. 9 (2021), 8, insges. 25 S.
Cell and molecular biology of thyroid disorders 2.0
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 4, insges. 6 S.
Microgravity and space medicine
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 13, insges. 7 S.
Kinase-inhibitors in iodine-refractory differentiated thyroid cancer - focus on occurrence, mechanisms, and management of treatment-related hypertension
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 22, insges. 23 S.
The CellBox-2 Mission to the International Space Station - thyroid cancer cells in space
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 16, insges. 21 S.
SARS-CoV-2 and hypertension
In: Physiological reports - [S.l.]: Wiley, 2013, Bd. 9 (2021), insges. 14 S.
Role of apoptosis in wound healing and apoptosis alterations in microgravity
In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, 2013, Bd. 9 (2021), insges. 22 S.
Alterations of growth and focal adhesion molecules in human breast cancer cells exposed to the random positioning machine
In: Frontiers in cell and developmental biology - Lausanne: Frontiers Media, 2013, Bd. 9 (2021), insges. 17 S.
Changes in exosomal miRNA composition in thyroid cancer cells after prolonged exposure to real microgravity in space
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 23, insges. 24 S.
Changes in exosome release in thyroid cancer cells after prolonged exposure to real microgravity in space
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 4, insges. 19 S.
2020
Begutachteter Zeitschriftenartikel
Multikinase inhibitor treatment in thyroid cancer
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 1, Art.-Nr. 10, insges. 19 Seiten
Insight in adhesion protein sialylation and microgravity dependent cell adhesion - an omics network approach
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 5, Art.-Nr. 1749, insges. 23 Seiten
Endothelin receptor antagonists - status quo and future perspectives for targeted therapy
In: Journal of Clinical Medicine - Basel: MDPI, 2012, Bd. 9.2020, 3, Art.-Nr. 824, insges. 29 Seiten
The effects of microgravity on differentiation and cell growth in stem cells and cancer stem cells
In: Stem cells translational medicine - Durham: AlphaMed Press, 2012, Bd. 9 (2020), 8, S. 882-894
The role of SOX family members in solid tumours and metastasis
In: Seminars in cancer biology - London: Academic Press, 1995, Bd. 67 (2020), 1, S. 122-153, 2019
Simulated microgravity influences VEGF, MAPK, and PAM signaling in prostate cancer cells
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 4, Art.-Nr. 1263, insges. 26 Seiten
Implications of altered endosome and lysosome biology in space environments
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 21, Art.-Nr. 8205, insgesamt 19 Seiten
Science between bioreactors and space research - response to comments by Joseph J. Bevelacqua et al. on Dexamethasone Inhibits Spheroid Formation of Thyroid Cancer Cells Exposed to Simulated Microgravity
In: Cells - Basel: MDPI, 2012, Vol. 9.2020, 8, Art.-Nr. 1763, insges. 3 Seiten
Potential beneficial effects of vitamin D in coronary artery disease
In: Nutrients - Basel: MDPI, 2009, Vol.12.2020, 1, Art.-Nr. 99, insges. 22 Seiten
The prostacyclin analogue treprostinil in the treatment of pulmonary arterial hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 126 (2020), 1, S. 32-42
Selective surgical treatment of the intraneural perineurioma of the femoral nerve by tumor resection and graft repair
In: Journal of case reports and medical images - Reno, NV: MedDocs Publishers LLC, 2018, Vol. 3.2020, 1, 1060, 5 Seiten
Dexamethasone inhibits spheroid formation of thyroid cancer cells exposed to simulated microgravity
In: Cells - Basel: MDPI, 2012, Vol. 9.2020, 2, Art.-Nr. 367, insges. 25 Seiten
Breast cancer cells in microgravity - new aspects for cancer research
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 19, Art.-Nr. 7345, insges. 22 Seiten
The vasoactive mas receptor in essential hypertension
In: Journal of Clinical Medicine - Basel: MDPI, 2012, Bd. 9.2020, 1, Art.-Nr. 267, insges. 12 Seiten
Exploration of space to achieve scientific breakthroughs
In: Biotechnology advances: research reviews and patent abstracts - Amsterdam: Elsevier Science Publ., 1983, Vol. 43.2020, Art.-Nr. 107572, insges. 33 Seiten
Influence of microgravity on apoptosis in cells, tissues, and other systems in vivo and in vitro
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 24, 9373, insgesamt 32 Seiten
An evaluation of the fixed-dose combination sacubitril/valsartan for the treatment of arterial hypertension
In: Expert opinion on pharmacotherapy - Abingdon, Oxon: Routledge, Taylor & Francis, Bd. 21 (2020), 10, S. 1133-1143
Tissue engineering of cartilage using a random positioning machine
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 24, 9596, insgesamt 24 Seiten
2019
Abstract
Growing tissues in space
In: Frontiers in physiology - Lausanne: Frontiers Research Foundation, 2007, Bd. 10.2019, Abstract 14, insges. 3 S.
Microgravity-based modulation of VEGF expression in human thyroid carcinoma cells
In: Frontiers in physiology - Lausanne: Frontiers Research Foundation, 2007, Bd. 10.2019, Abstract 2, insges. 4 S.
Alterations of the cytoskeleton in breast cancer cells during microgravity visualised by FLUMIAS live-cell imaging
In: Frontiers in physiology - Lausanne: Frontiers Research Foundation, 2007, Bd. 10.2019, Abstract 8, insges. 3 S.
Begutachteter Zeitschriftenartikel
Augmenting cancer cell proteomics with cellular images - a semantic approach to understand focal adhesion
In: Journal of biomedical informatics - San Diego, Calif.: Academic Press, Bd. 100.2019, Art.-Nr. 103320
Tyrosine kinase inhibitor-induced hypertension - role of hypertension as a biomarker in cancer treatment
In: Current vascular pharmacology - Hilversum [u.a.]: Bentham Science Publ., Bd. 17 (2019), 6, S. 618-634
Morphological and molecular changes in juvenile normal human fibroblasts exposed to simulated microgravity
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 9.2019, Art.-Nr. 11882, insges. 22 S.
Bioactive candy - effects of licorice on the cardiovascular system
In: Foods - Basel: MDPI, 2012, Bd.8.2019, 10, Art.-Nr. 495, insges. 20 Seiten
Cell and molecular biology of thyroid disorders
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd.20.2019, 12, Art.-Nr. 2895, insges. 8 S.
Guest edited collection - gravitational biology and space medicine
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd.9.2019, Art.-Nr. 14399, insges. 4 S.
The effects of oral L-arginine and L-citrulline supplementation on blood pressure
In: Nutrients - Basel: MDPI, 2009, Bd. 11.2019, 7, Art.-Nr. 1679, insges. 14 S.
Fighting thyroid cancer with microgravity research
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 20.2019, 10, Art.-Nr. 2553, insges. 21 S.
Growing blood vessels in space - preparation studies of the SPHEROIDS project using related ground-based studies
In: Acta astronautica - Amsterdam [u.a.]: Elsevier Science, Bd. 159 (2019), S. 267-272
Growth of endothelial cells in space and in simulated microgravity - a comparison on the secretory level
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 52 (2019), 5, S. 1039-1060
Beneficial effects of low frequency vibration on human chondrocytes in vitro
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 53 (2019), 4, S. 623-637
Changes in human foetal osteoblasts exposed to the random positioning machine and bone construct tissue engineering
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 20.2019, 6, Art.-Nr. 1357, insges. 26 S.
Drug-induced hypertension caused by multikinase inhibitors (sorafenib, sunitinib, lenvatinib and axitinib) in renal cell carcinoma treatment
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd.20.2019, 19, Art.-Nr. 4712, insges. 23 Seiten
Real microgravity influences the cytoskeleton and focal adhesions in human breast cancer cells
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 20.2019, 13, Art.-Nr. 3156, insges. 25 S.
Short-term microgravity influences cell adhesion in human breast cancer cells
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 20.2019, 22, Art.-Nr. 5730, insges. 27 Seiten
Nebivolol in the treatment of arterial hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 125 (2019), 3, S. 189-201
Current knowledge about the impact of microgravity on the proteome
In: Expert review of proteomics - Abingdon: Taylor & Francis Group, Bd. 16 (2019), 1, S. 5-16
A focus on riociguat in the treatment of pulmonary arterial hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 125 (2019), 3, S. 202-214
2018
Begutachteter Zeitschriftenartikel
Semantic analysis of posttranslational modification of proteins accumulated in thyroid cancer cells exposed to simulated microgravity
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 19.2018, 8, Art.-Nr. 2257, insges. 16 S.
A focus on macitentan in the treatment of pulmonary arterial hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 123 (2018), 2, S. 103-113
Key proteins involved in spheroid formation and angiogenesis in endothelial cells after long-term exposure to simulated microgravity
In: Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry and pharmacology - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 45 (2018), 2, S. 429-445
Tissue engineering under microgravity conditions - use of stem cells and specialized cells
In: Stem Cells and Development - Larchmont, NY: Liebert, Bd. 27 (2018), 12, S. 787-804
Microgravity affects thyroid cancer cells during the TEXUS-53 mission stronger than hypergravity
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 19.2018, 12, Art.-Nr. 4001, insges. 20 S.
The role of NF[kappa]B in spheroid formation of human breast cancer cells cultured on the Random Positioning Machine
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 8.2018, Art.-Nr. 921, insges. 17 S.
Thyroid cancer cells in space during the TEXUS-53 sounding rocket mission - the THYROID project
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 8.2018, Art.-Nr. 10355, insges. 13 S.
The impact of vitamin D in the treatment of essential hypertension
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 19.2018, 2, Art.-Nr. 455, insges. 14 S.
Pathway analysis hints towards beneficial effects of long-term vibration on human chondrocytes
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 47 (2018), 4, S. 1729-1741
Pazopanib, cabozantinib, and vandetanib in the treatment of progressive medullary thyroid cancer with a special focus on the adverse effects on hypertension
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 19.2018, 10, Art.-Nr. 3258, insges. 15 S.
The combination of valsartan and sacubitril in the treatment of hypertension and heart failure - an update
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 122 (2018), 1, S. 9-18
Current and future treatments for persistent pulmonary hypertension in the newborn
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, 2004, Bd. 123 (2018), 4, S. 392-406
Decreased E-cadherin in MCF7 human breast cancer cells forming multicellular spheroids exposed to simulated microgravity
In: Proteomics - Weinheim: Wiley VCH, Bd. 18.2018, 13, Art.-Nr. e1800015
2017
Begutachteter Zeitschriftenartikel
The adverse effect of hypertension in the treatment of thyroid cancer with multi-kinase inhibitors
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 18.2017, 3, Art.-Nr. 625, insges. 19 S.
Proteome analysis of human follicular thyroid cancer cells exposed to the random positioning machine
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 18.2017, 3, Art.-Nr. 546, insges. 13 S.
Hypertension caused by lenvatinib and everolimus in the treatment of metastatic renal cell carcinoma
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 18.2017, 8, Art.-Nr. 1736, insges. 12 S.
Azilsartan medoxomil, an angiotensin II receptor antagonist for the treatment of hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, 2004, Bd. 121.2017, 4, S. 225-233
Three-dimensional growth of human endothelial cells in an automated cell culture experiment container during the SpaceX CRS-8 ISS space mission - the SPHEROIDS project
In: Biomaterials - Amsterdam [u.a.]: Elsevier Science, 1980, Bd. 124.2017, S. 126-156
Preparation of A spaceflight - apoptosis search in sutured wound healing models
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 18.2017, 12, Art.-Nr. 2604, insges. 22 S.
A special focus on selexipag - treatment of pulmonary arterial hypertension
In: Current pharmaceutical design: dispatches from the front line of drug design - Hilversum: Bentham Science Publ., 2000, Bd. 23.2017, 34, S. 5191-5199
Cytokine release and focal adhesion proteins in normal thyroid cells cultured on the random positioning machine
In: Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry and pharmacology - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 43.2017, 1, S. 257-270
Buchbeitrag
Cancer research in space
In: Biotechnology in Space - Cham: Springer, 2017 . - 2017, S. 87-106
Tissue engineering in microgravity
In: Biotechnology in Space - Cham: Springer, 2017 . - 2017, S. 73-85
2016
Begutachteter Zeitschriftenartikel
Scaffold-free tissue formation under real and simulated microgravity conditions
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, 2004, Bd. 119.2016, Suppl.3, Seite 26-33
Tissue engineering of cartilage on ground-based facilities
In: Microgravity science and technology: international journal for microgravity research and applications - Heidelberg: Springer, 2007, Bd. 28.2016, 3, S. 237-245
LCZ696 (valsartan/sacubitril) - a possible new treatment for hypertension and heart failure
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, 2004, Bd. 118.2016, 1, S. 14-22
Annotated gene and proteome data support recognition of interconnections between the results of different experiments in space research
In: Microgravity science and technology - Heidelberg: Springer, 2007, Bd. 28.2016, 3, S. 357-365
Alterations of the cytoskeleton in human cells in space proved by life-cell imaging
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 6.2016, Art.-Nr. 20043, insges. 14 S.
Reduced expression of cytoskeletal and extracellular matrix genes in human adult retinal pigment epithelium cells exposed to simulated microgravity
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 40.2016, 1/2, S. 1-17
Latest results for anti-angiogenic drugs in cancer treatment
In: Current pharmaceutical design - Hilversum: Bentham Science Publ, 2000, Bd. 22.2016, 39, S. 5927-5942
The impact of microgravity on bone in humans
In: Bone: cell molecular biology, pathophysiology, treatment ; official journal of the International Bone and Mineral Society - Amsterdam [u.a.]: Elsevier Science, 1985, Bd. 87.2016, S. 44-56
Identifications of novel mechanisms in breast cancer cells involving duct-like multicellular spheroid formation after exposure to the Random Positioning Machine
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 6.2016, Art.-Nr. 26887, insges. 18 S.
Effects and role of multikinase inhibitors in thyroid cancer
In: Current pharmaceutical design - Hilversum: Bentham Science Publ, 2000, Bd. 22.2016, 39, S. 5915-5926
Pathways regulating spheroid formation of human follicular thyroid cancer cells under simulated microgravity conditions - A genetic approach
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 17 (2016), 4, Art.-Nr. 528, insges. 20 S.
Thyroid cells exposed to simulated microgravity conditions - comparison of the fast rotating clinostat and the random positioning machine
In: Microgravity science and technology - Heidelberg: Springer, 2007, Bd. 28.2016, 3, S. 247-260
The impact of hypergravity and vibration on gene and protein expression of thyroid cells
In: Microgravity science and technology - Heidelberg: Springer, 2007, Bd. 28.2016, 3, S. 261-274
2015
Begutachteter Zeitschriftenartikel
Moderate alterations of the cytoskeleton in human chondrocytes after short-term microgravity produced by parabolic flight maneuvers could be prevented by up-regulation of BMP-2 and SOX-9
In: The FASEB journal - Bethesda, Md: FASEB, 1987, Bd. 29.2015, 6, S. 2303-2314
Third-generation beta-adrenoceptor antagonists in the treatment of hypertension and heart failure
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, 2004, Bd. 117.2015, 1, S. 5-14
Mechanisms of three-dimensional growth of thyroid cells during long-term simulated microgravity
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, Bd. 5.2015, Art.-Nr. 16691, insges. 17 S.
Anti-angiogenic drugs in the treatment of metastatic renal cell carcinoma - Advances in clinical application
In: Current vascular pharmacology - Hilversum [u.a.]: Bentham Science Publ., Bd. 13 (2015), 3, S. 381-391
Identification of proteins involved in inhibition of spheroid formation under microgravity
In: Proteomics - Weinheim: Wiley VCH, 2001, Bd. 15.2015, 17, S. 2945-2952
The importance of caveolin-1 as key-regulator of three-dimensional growth in thyroid cancer cells cultured under real and simulated microgravity conditions
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, Bd. 16 (2015), 12, S. 28296-28310
Common effects on cancer cells exerted by a random positioning machine and a 2D clinostat
In: PLOS ONE - San Francisco, California, US: PLOS, Bd. 10.2015, 8, Art. e0135157, insges. 22 S.
Differential gene expression of human chondrocytes cultured under short-term altered gravity conditions during parabolic flight maneuvers
In: Cell communication and signaling - London: Biomed Central, Bd. 13.2015, Art.-Nr. 18, insges. 13 S.
2014
Begutachteter Zeitschriftenartikel
Growing Tissues in Real and Simulated Microgravity: New Methods for Tissue Engineering
In: Tissue Engineering Part B: Reviews, Mary Ann Liebert Inc, 2014, Bd. 20, Heft 6, S. 555-566
The impact of microgravity-based proteomics research
In: Expert review of proteomics - Abingdon: Taylor & Francis Group, 2004, Bd. 11.2014, 4, S. 465-476
Mechanisms of apoptosis in irradiated and sunitinib-treated follicular thyroid cancer cells
In: Apoptosis - Dordrecht [u.a.]: Springer Science + Business Media B.V, 1996, Bd. 19.2014, 3, S. 480-490
Anti-Vascular Endothelial Growth Factor Therapy in Breast Cancer
In: International Journal of Molecular Sciences, MDPI AG, 2014, Bd. 15, Heft 12, S. 23024-23041
Differential gene expression profile and altered cytokine secretion of thyroid cancer cells in space
In: The FASEB Journal, Wiley, 2014, Bd. 28, Heft 2, S. 813-835
Proteomic differences between microvascular endothelial cells and the EA.hy926 cell line forming three-dimensional structures
In: Proteomics - Weinheim: Wiley VCH, 2001, Bd. 14.2014, 6, S. 689-698
The impact of simulated and real microgravity on bone cells and mesenchymal stem cells
In: BioMed research international - New York [u.a.]: Hindawi, 2014, Art.-ID 928507, insges. 15 S.
Spheroid formation of human thyroid cancer cells under simulated microgravity - a possible role of CTGF and CAV1
In: Cell communication and signaling - London: Biomed Central, 2003, Bd. 12.2014, Art.-Nr. 32, insges. 11 S.
2013
Begutachteter Zeitschriftenartikel
Changes in morphology, gene expression and protein content in chondrocytes cultured on a random positioning machine
In: PLOS ONE - San Francisco, California, US: PLOS, Bd. 8.2013, 11, Art.-Nr. e79057, insges. 8 S.
Biotechnologische Nutzung der Schwerelosigkeit für medizinische Forschung - Analyse humaner Zellen nach Schwerelosigkeit : analysis of human cells after weightlessness
In: Flugmedizin, Tropenmedizin, Reisemedizin - Stuttgart: Thieme, Bd. 20 (2013), 4, S. 173-178
Impact of sunitinib on human thyroid cancer cells
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, Bd. 32 (2013), 1, S. 154-170
Genomic approach to identify factors that drive the formation of three-dimensional structures by EA.hy926 endothelial cells
In: PLoS one. - Lawrence, Kan : PLoS, Bd. 8.2013, 5, insges. 10 S.
Interleukin-6 expression under gravitational stress due to vibration and hypergravity in follicular thyroid cancer cells
In: PLOS ONE - San Francisco, California, US: PLOS, Bd. 8.2013, 7, Art.-Nr. e68140, insges. 12 S.
Interaction of proteins identified in human thyroid cells
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 14.2013, 1, S. 1164-1178
Spheroid formation of human thyroid cancer cells in an automated culturing system during the Shenzhou-8 Space mission
In: Biomaterials - Amsterdam [u.a.]: Elsevier Science, Bd. 34 (2013), 31, S. 7694-7705
Biomarkers for anti-angiogenic therapy in cancer
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 14.2013, 5, S. 9338-9364
The impact of altered gravity and vibration on endothelial cells during a parabolic flight
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, Bd. 31 (2013), 2/3, S. 432-451
2012
Originalartikel in begutachteter internationaler Zeitschrift
Gravity-sensitive signaling drives 3-dimensional formation of multicellular thyroid cancer spheroids
In: The FASEB journal/ Federation of American Societies for Experimental Biology - Bethesda, Md.: FASEB, Bd. 26 (2012), 12, S. 5124-5140
Short-term weightlessness produced by parabolic flight maneuvers altered gene expression patterns in human endothelial cells
In: The FASEB journal/ Federation of American Societies for Experimental Biology - Bethesda, Md.: FASEB, Bd. 26 (2012), 2, S. 639-655
The use of sigmoid pH gradients in free-flow isoelectric focusing of human endothelial cell proteins
In: Electrophoresis: electrokinetics, fluidics, proteomics - Weinheim: Wiley-VCH, 1980, Bd. 33.2012, 9/10, S. 1349-1355
Gene networks modified by sulphonylureas in beta cells: A pathway-based analysis of insulin secretion and cell death
In: Basic & clinical pharmacology & toxicology: BCPT / publ. by the Nordic Pharmacological Society: BCPT - Malden, Mass.: Wiley-Blackwell, 2004, Bd. 111.2012, 4, S. 254-261
Metabolic enzyme diversity in different human thyroid cell lines and their sensitivity to gravitational forces
In: Proteomics: proteomics and systems biology - Weinheim: Wiley-VCH, 2001, Bd. 12.2012, 15/16, S. 2539-2546
Target-based anti-angiogenic therapy in breast cancer
In: Current pharmaceutical design: a timely review journal on recent advances in drug design - Hilversum: Bentham Science Publ., Bd. 18 (2012), 27, S. 4244-4257
The effects of newer beta-adrenoceptor antagonists on vascular function in cardiovascular disease
In: Current vascular pharmacology: the journal for current and in-depth reviews on vascular pharmacology - San Francisco, Calif.: Bentham, 2003, Bd. 10.2012, 3, S. 378-390
2011
Originalartikel in begutachteter internationaler Zeitschrift
Differential gene regulation under altered gravity conditions in follicular thyroid cancer cells: relationship between the extracellular matrix and the cytoskeleton
In: Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry and pharmacology - Basel: Karger, Bd. 28 (2011), 2, S. 185-198
Abgeschlossene Projekte
- Effekte der Schwerelosigkeit auf Gefäß- und Sphäroidbildung humaner Zellen sowie auf Wundheilung und Herzmorphologie
Laufzeit: 01.03.2019 - 28.02.2022
- Universität Köln, Genomforschungscenter, Prof. Dr. Michael Nothnagel,