ABTEILUNG MIKROGRAVITATION UND TRANSLATIONALE REGENERATIVE MEDIZIN

Dr. rer. nat. Marcus Krüger

AG-Leiter

Dr. rer. nat. Marcus Krüger

Abteilung Mikrogravitation und Translationale Regenerative Medizin (MTRM)
AG Umweltzellbiologie
Universitätsplatz 2, 39106 Magdeburg, G28-110
Publikationen

2024

Begutachteter Zeitschriftenartikel

Abdelfattah, Fatima; Schulz, Herbert; Wehland, Markus; Corydon, Thomas J.; Sahana, Jayashree; Kraus, Armin; Krüger, Marcus; González-Torres, Luis Fernando; Cortés-Sánchez, José Luis; Wise, Petra; Mushunuri, Ashwini; Hemmersbach, Ruth; Liemersdorf, Christian; Infanger, Manfred; Grimm, Daniela

Omics studies of specialized cells and stem cells under microgravity conditions
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 25 (2024), Heft 18, Artikel 10014, insges. 58 S.

Begutachteter Zeitschriftenartikel

Graf, Jenny; Schulz, Herbert; Wehland, Markus; Corydon, Thomas J.; Sahana, Jayashree; Abdelfattah, Fatima; Wuest, Simon L.; Egli, Marcel; Krüger, Marcus; Kraus, Armin; Wise, Petra; Infanger, Manfred; Grimm, Daniela

Omics studies of tumor cells under microgravity conditions
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 25 (2024), Heft 2, Artikel 926, insges. 48 S.

Begutachteter Zeitschriftenartikel

Krüger, Julia; Richter, Peter; Stoltze, Julia; Prasad, Binod; Strauch, Sebastian M.; Krüger, Marcus; Nasir, Adeel; Lebert, Michael

Changes in gravitaxis and gene-expression in an Euglena gracilis culture over time
In: Biomolecules - Basel : MDPI, Bd. 14 (2024), Heft 3, Artikel 327, insges. 15 S.

Begutachteter Zeitschriftenartikel

Barkia, Balkis; Sandt, Viviann; Melnik, Daniela; Cortés-Sánchez, José Luis; Marchal, Shannon; Baselet, Bjorn; Baatout, Sarah; Sahana, Jayashree; Grimm, Daniela; Wehland, Markus; Schulz, Herbert; Infanger, Manfred; Kraus, Armin; Krüger, Marcus

The formation of stable lung tumor spheroids during random positioning involves increased estrogen sensitivity
In: Biomolecules - Basel : MDPI, Bd. 14 (2024), Heft 10, Artikel 1292, insges. 17 S.

2023

Begutachteter Zeitschriftenartikel

Cortés-Sánchez, José Luis; Melnik, Daniela; Sandt, Viviann; Kahlert, Stefan; Marchal, Shannon; Johnson, Ian R. D.; Calvaruso, Marco; Liemersdorf, Christian; Wuest, Simon L.; Grimm, Daniela; Krüger, Marcus

Fluid and bubble flow detach adherent cancer cells to form spheroids on a random positioning machine
In: Cells - Basel : MDPI, Bd. 12 (2023), Heft 22, Artikel 2665, insges. 27 S.

Begutachteter Zeitschriftenartikel

Melnik, Daniela; Cortés-Sánchez, José Luis; Sandt, Viviann; Kahlert, Stefan; Kopp, Sascha; Grimm, Daniela; Krüger, Marcus

Dexamethasone selectively inhibits detachment of metastatic thyroid cancer cells during random positioning
In: Cancers - Basel : MDPI, Bd. 15 (2023), Heft 6, Artikel 1641, insges. 25 S.

Begutachteter Zeitschriftenartikel

Krüger, Marcus; Kopp, Sascha

Tumor models and drug targeting in vitro - where are we today? : Where do we go from here?
In: Cancers - Basel : MDPI, Bd. 15 (2023), Heft 6, Artikel 1768, insges. 5 S.

Begutachteter Zeitschriftenartikel

Corydon, Thomas J.; Schulz, Herbert; Richter, Peter; Strauch, Sebastian M.; Böhmer, Maik; Ricciardi, Dario A.; Wehland, Markus; Krüger, Marcus; Erzinger, Gilmar S.; Lebert, Michael; Infanger, Manfred; Wise, Petra; Grimm, Daniela

Current knowledge about the impact of microgravity on gene regulation
In: Cells - Basel : MDPI, Bd. 12 (2023), Heft 7, Artikel 1043, insges. 59 S.

Begutachteter Zeitschriftenartikel

Krüger, Marcus

Remove, refine, reduce - cell death in biological systems
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 24 (2023), Heft 8, Artikel 7028, insges. 5 S.

Begutachteter Zeitschriftenartikel

Miranda, Silvana; Marchal, Shannon; Cumps, Lina; Dierckx, Jenne; Krüger, Marcus; Grimm, Daniela; Baatout, Sarah; Tabury, Kevin; Baselet, Bjorn

A dusty road for astronauts
In: Biomedicines - Basel : MDPI, Bd. 11 (2023), Heft 7, Artikel 1921, insges. 21 S.

2022

Begutachteter Zeitschriftenartikel

Cortés-Sánchez, José Luis; Callant, Jonas; Krüger, Marcus; Sahana, Jayashree; Kraus, Armin; Baselet, Bjorn; Infanger, Manfred; Baatout, Sarah; Grimm, Daniela

Cancer studies under space conditions - finding answers abroad
In: Biomedicines - Basel : MDPI, Bd. 10 (2022), Heft 1, Artikel 25, insges. 28 S.

Begutachteter Zeitschriftenartikel

Grimm, Daniela; Schulz, Herbert; Krüger, Marcus; Cortés-Sánchez, José Luis; Egli, Marcel; Kraus, Armin; Sahana, Jayashree; Corydon, Thomas J.; Hemmersbach, Ruth; Wise, Petra; Infanger, Manfred; Wehland, Markus

The fight against cancer by microgravity - the multicellular spheroid as a metastasis model
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 23 (2022), Heft 6, Artikel 3073, insges. 45 S.

Begutachteter Zeitschriftenartikel

Dietrichs, Dorothea; Grimm, Daniela; Sahana, Jayashree; Melnik, Daniela; Corydon, Thomas J.; Wehland, Markus; Krüger, Marcus; Vermeesen, Randy; Baselet, Bjorn; Baatout, Sarah; Hybel, Trine Engelbrecht; Kahlert, Stefan; Schulz, Herbert; Infanger, Manfred; Kopp, Sascha

Three-dimensional growth of prostate cancer cells exposed to simulated microgravity
In: Frontiers in cell and developmental biology - Lausanne : Frontiers Media, Bd. 10 (2022), Artikel 841017, insges. 21 S.

Begutachteter Zeitschriftenartikel

Akif, Faheem Ahmad; Mahmoud, Mona; Prasad, Binod; Richter, Peter; Azizullah, Azizullah; Qasim, Muhammad; Anees, Muhammad; Krüger, Marcus; Gastiger, Susanne; Burkovski, Andreas; Strauch, Sebastian M.; Lebert, Michael

Polyethylenimine increases antibacterial efficiency of chlorophyllin
In: Antibiotics - Basel: MDPI, 2012, Bd. 11 (2022), 10, insges. 15 S.

Begutachteter Zeitschriftenartikel

Krüger, Marcus; Richter, Peter

To die or not to die - cell death in biology and disease
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 23 (2022), Heft 12, Artikel 6734, insges. 3 S.

Begutachteter Zeitschriftenartikel

Schulz, Herbert; Strauch, Sebastian M.; Richter, Peter; Wehland, Markus; Krüger, Marcus; Sahana, Jayashree; Corydon, Thomas J.; Wise, Petra; Baran, Ronni; Lebert, Michael; Grimm, Daniela

Latest knowledge about changes in the proteome in microgravity
In: Expert review of proteomics - Abingdon : Taylor & Francis Group, Bd. 19 (2022), Heft 1, S. 43-59

2021

Begutachteter Zeitschriftenartikel

Krüger, Marcus; Richter, Peter; Strauch, Sebastian M.

Natural products in modern biology - ancient wisdom for todays challenges
In: Biology - Basel : MDPI, Bd. 10 (2021), Heft 5, Artikel 369, insges. 3 S.

Begutachteter Zeitschriftenartikel

Wise, Petra; Neviani, Paolo; Riwaldt, Stefan; Corydon, Thomas Juhl; Wehland, Markus; Braun, Markus; Krüger, Marcus; Infanger, Manfred; Grimm, Daniela

Changes in exosome release in thyroid cancer cells after prolonged exposure to real microgravity in space
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 4, insges. 19 S.

Begutachteter Zeitschriftenartikel

Wise, Petra; Neviani, Paolo; Riwaldt, Stefan; Corydon, Thomas J.; Wehland, Markus; Braun, Markus; Krüger, Marcus; Infanger, Manfred; Grimm, Daniela Gabriele

Changes in exosomal miRNA composition in thyroid cancer cells after prolonged exposure to real microgravity in space
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 23, insges. 24 S.

Begutachteter Zeitschriftenartikel

Melnik, Daniela; Krüger, Marcus; Schulz, Herbert; Kopp, Sascha; Wehland, Markus; Bauer, Johann; Baselet, Bjorn; Vermeesen, Randy; Baatout, Sarah; Corydon, Thomas J.; Infanger, Manfred; Grimm, Daniela Gabriele

The CellBox-2 Mission to the International Space Station - thyroid cancer cells in space
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 16, insges. 21 S.

Begutachteter Zeitschriftenartikel

Riwaldt, Stefan; Corydon, Thomas J.; Pantalone, Desiré; Sahana, Jayashree; Wise, Petra; Wehland, Markus; Krüger, Marcus; Melnik, Daniela; Kopp, Sascha; Infanger, Manfred; Grimm, Daniela

Role of apoptosis in wound healing and apoptosis alterations in microgravity
In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, 2013, Bd. 9 (2021), insges. 22 S.

Begutachteter Zeitschriftenartikel

Sahana, Jayashree; Corydon, Thomas J.; Wehland, Markus; Krüger, Marcus; Kopp, Sascha; Melnik, Daniela; Kahlert, Stefan; Relja, Borna; Infanger, Manfred; Grimm, Daniela Gabriele

Alterations of growth and focal adhesion molecules in human breast cancer cells exposed to the random positioning machine
In: Frontiers in cell and developmental biology - Lausanne: Frontiers Media, 2013, Bd. 9 (2021), insges. 17 S.

Begutachteter Zeitschriftenartikel

Kaae, Anne Christine; Kreißl, Michael; Krüger, Marcus; Infanger, Manfred; Grimm, Daniela Gabriele; Wehland, Markus

Kinase-inhibitors in iodine-refractory differentiated thyroid cancer - focus on occurrence, mechanisms, and management of treatment-related hypertension
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 22, insges. 23 S.

Begutachteter Zeitschriftenartikel

Ravichandran, Briyanth; Grimm, Daniela Gabriele; Krüger, Marcus; Kopp, Sascha; Infanger, Manfred; Wehland, Markus

SARS-CoV-2 and hypertension
In: Physiological reports - [S.l.]: Wiley, 2013, Bd. 9 (2021), insges. 14 S.

2020

Begutachteter Zeitschriftenartikel

Krüger, Marcus; Kopp, Sascha; Wehland, Markus; Corydon, Thomas J.; Grimm, Daniela Gabriele

Science between bioreactors and space research - response to comments by Joseph J. Bevelacqua et al. on Dexamethasone Inhibits Spheroid Formation of Thyroid Cancer Cells Exposed to Simulated Microgravity
In: Cells - Basel: MDPI, 2012, Vol. 9.2020, 8, Art.-Nr. 1763, insges. 3 Seiten

Begutachteter Zeitschriftenartikel

Grimm, Daniela Gabriele; Bauer, Johann; Wise, Petra; Krüger, Marcus; Simonsen, Ulf; Wehland, Markus; Infanger, Manfred; Corydon, Thomas J.

The role of SOX family members in solid tumours and metastasis
In: Seminars in cancer biology - London: Academic Press, 1995, Bd. 67 (2020), 1, S. 122-153, 2019

Begutachteter Zeitschriftenartikel

Prasad, Binod; Grimm, Daniela Gabriele; Strauch, Sebastian M.; Erzinger, Gilmar S.; Corydon, Thomas J.; Lebert, Michael; Magnusson, Nils E.; Infanger, Manfred; Richter, Peter; Krüger, Marcus

Influence of microgravity on apoptosis in cells, tissues, and other systems in vivo and in vitro
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 24, 9373, insgesamt 32 Seiten

Begutachteter Zeitschriftenartikel

Dieteren, Scott; Franz, Niklas; Köhler, Kernt; Nowak, Aleksander; Ehnert, Sabrina; Surov, Alexey; Krüger, Marcus; Marzi, Ingo; Wagner, Nils; Relja, Borna

Ethyl pyruvate reduces systemic leukocyte activation via caspase-1 and NF-[kappa]B after blunt chest trauma and haemorrhagic shock
In: Frontiers in medicine - Lausanne: Frontiers Media, 2014, Bd. 7.2020, Art.-Nr. 562904, insgesamt 11 Seiten

Begutachteter Zeitschriftenartikel

Nassef, Mohamed Zakaria; Melnik, Daniela; Kopp, Sascha; Sahana, Jayashree; Infanger, Manfred; Lützenberg, Ronald; Relja, Borna; Wehland, Markus; Grimm, Daniela; Krüger, Marcus

Breast cancer cells in microgravity - new aspects for cancer research
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 19, Art.-Nr. 7345, insges. 22 Seiten

Begutachteter Zeitschriftenartikel

Melnik, Daniela; Sahana, Jayashree; Corydon, Thomas J.; Kopp, Sascha; Nassef, Mohamed Zakaria; Wehland, Markus; Infanger, Manfred; Grimm, Daniela; Krüger, Marcus

Dexamethasone inhibits spheroid formation of thyroid cancer cells exposed to simulated microgravity
In: Cells - Basel: MDPI, 2012, Vol. 9.2020, 2, Art.-Nr. 367, insges. 25 Seiten

Begutachteter Zeitschriftenartikel

Ancker, Ole Vincent; Krüger, Marcus; Wehland, Markus; Infanger, Manfred; Grimm, Daniela Gabriele

Multikinase inhibitor treatment in thyroid cancer
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 1, Art.-Nr. 10, insges. 19 Seiten

Begutachteter Zeitschriftenartikel

Povlsen, Amalie L.; Grimm, Daniela Gabriele; Wehland, Markus; Infanger, Manfred; Krüger, Marcus

The vasoactive mas receptor in essential hypertension
In: Journal of Clinical Medicine - Basel: MDPI, 2012, Bd. 9.2020, 1, Art.-Nr. 267, insges. 12 Seiten

Begutachteter Zeitschriftenartikel

Lindegaard Pedersen, Mia; Krüger, Marcus; Grimm, Daniela Gabriele; Infanger, Manfred; Wehland, Markus

The prostacyclin analogue treprostinil in the treatment of pulmonary arterial hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 126 (2020), 1, S. 32-42

Begutachteter Zeitschriftenartikel

Prasad, Binod; Richter, Peter; Vadakedath, Nithya; Mancinelli, Rocco; Krüger, Marcus; Strauch, Sebastian M.; Grimm, Daniela Gabriele; Darriet, Philippe; Chapel, Jean-Paul; Cohen, Jacob; Lebert, Michael

Exploration of space to achieve scientific breakthroughs
In: Biotechnology advances : research reviews and patent abstracts - Amsterdam : Elsevier Science Publ. - Vol. 43.2020, Art.-Nr. 107572, insges. 33 Seiten

Begutachteter Zeitschriftenartikel

Grimm, Daniela Gabriele; Wehland, Markus; Corydon, Thomas J.; Richter, Peter; Prasad, Binod; Bauer, Johann; Egli, Marcel; Kopp, Sascha; Lebert, Michael; Krüger, Marcus

The effects of microgravity on differentiation and cell growth in stem cells and cancer stem cells
In: Stem cells translational medicine - Durham: AlphaMed Press, 2012, Bd. 9 (2020), 8, S. 882-894

Begutachteter Zeitschriftenartikel

Enevoldsen, Frederik C.; Sahana, Jayashree; Wehland, Markus; Grimm, Daniela; Infanger, Manfred; Krüger, Marcus

Endothelin receptor antagonists - status quo and future perspectives for targeted therapy
In: Journal of Clinical Medicine - Basel: MDPI, 2012, Bd. 9.2020, 3, Art.-Nr. 824, insges. 29 Seiten

Begutachteter Zeitschriftenartikel

Wehland, Markus; Simonsen, Ulf; Buus, Niels Henrik; Krüger, Marcus; Grimm, Daniela Gabriele

An evaluation of the fixed-dose combination sacubitril/valsartan for the treatment of arterial hypertension
In: Expert opinion on pharmacotherapy - Abingdon, Oxon: Routledge, Taylor & Francis, Bd. 21 (2020), 10, S. 1133-1143

Begutachteter Zeitschriftenartikel

Hybel, Trine Engelbrecht; Dietrichs, Dorothea; Sahana, Jayashree; Corydon, Thomas J.; Nassef, Mohamed Zakaria; Wehland, Markus; Krüger, Marcus; Magnusson, Nils E.; Bauer, Johann; Utpatel, Kirsten; Infanger, Manfred; Grimm, Daniela; Kopp, Sascha

Simulated microgravity influences VEGF, MAPK, and PAM signaling in prostate cancer cells
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 4, Art.-Nr. 1263, insges. 26 Seiten

Begutachteter Zeitschriftenartikel

Legarth, Christian; Grimm, Daniela; Krüger, Marcus; Infanger, Manfred; Wehland, Markus

Potential beneficial effects of vitamin D in coronary artery disease
In: Nutrients - Basel: MDPI, 2009, Vol.12.2020, 1, Art.-Nr. 99, insges. 22 Seiten

2019

Abstract

Kopp, Sascha; Krüger, Marcus; Wehland, Markus; Bauer, Johann; Dittrich, Anita; Infanger, Manfred; Grimm, Daniela Gabriele

Growing tissues in space
In: Frontiers in physiology - Lausanne: Frontiers Research Foundation, 2007, Bd. 10.2019, Abstract 14, insges. 3 S.

Abstract

Nassef, Mohamed Z.; Kopp, Sascha; Melnik, Daniela; Krüger, Marcus; Wehland, Markus; Corydon, Thomas J.; Bauer, Johann; Infanger, Manfred; Grimm, Daniela Gabriele

Alterations of the cytoskeleton in breast cancer cells during microgravity visualised by FLUMIAS live-cell imaging
In: Frontiers in physiology - Lausanne: Frontiers Research Foundation, 2007, Bd. 10.2019, Abstract 8, insges. 3 S.

Abstract

Melnik, Daniela; Krüger, Marcus; Kopp, Sascha; Wehland, Markus; Bauer, Johann; Infanger, Manfred; Grimm, Daniela Gabriele

Microgravity-based modulation of VEGF expression in human thyroid carcinoma cells
In: Frontiers in physiology - Lausanne: Frontiers Research Foundation, 2007, Bd. 10.2019, Abstract 2, insges. 4 S.

Begutachteter Zeitschriftenartikel

Nassef, Mohamed Zakaria; Kopp, Sascha; Melnik, Daniela; Corydon, Thomas J.; Sahana, Jayashree; Krüger, Marcus; Wehland, Markus; Bauer, Thomas J.; Liemersdorf, Christian; Hemmersbach, Ruth; Infanger, Manfred; Grimm, Daniela

Short-term microgravity influences cell adhesion in human breast cancer cells
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 20.2019, 22, Art.-Nr. 5730, insges. 27 Seiten

Begutachteter Zeitschriftenartikel

Strauch, Sebastian M.; Grimm, Daniela; Corydon, Thomas J.; Krüger, Marcus; Bauer, Johann; Lebert, Michael; Wise, Petra; Infanger, Manfred; Richter, Peter

Current knowledge about the impact of microgravity on the proteome
In: Expert review of proteomics - Abingdon: Taylor & Francis Group, Bd. 16 (2019), 1, S. 5-16

Begutachteter Zeitschriftenartikel

Budolfsen, Cecilie; Faber, Julie; Grimm, Daniela Gabriele; Krüger, Marcus; Bauer, Johann; Wehland, Markus; Infanger, Manfred; Magnusson, Nils Erik

Tyrosine kinase inhibitor-induced hypertension - role of hypertension as a biomarker in cancer treatment
In: Current vascular pharmacology - Hilversum [u.a.]: Bentham Science Publ., Bd. 17 (2019), 6, S. 618-634

Begutachteter Zeitschriftenartikel

Krüger, Marcus; Richter, Peter; Strauch, Sebastian M.; Nasir, Adeel; Burkovski, Andreas; Antunes, Camila A.; Meißgeier, Tina; Schlücker, Eberhard; Schwab, Stefan; Lebert, Michael

What an Escherichia coli mutant can teach us about the antibacterial effect of chlorophyllin
In: Microorganisms - Basel: MDPI, Bd. 7.2019, 2, Art.-Nr. 59, insges. 23 S.

Begutachteter Zeitschriftenartikel

Mann, Vivek; Grimm, Daniela Gabriele; Corydon, Thomas J.; Krüger, Marcus; Wehland, Markus; Riwaldt, Stefan; Sahana, Jayashree; Kopp, Sascha; Bauer, Johann; Reseland, Janne E.; Infanger, Manfred; Lian, Aina Mari; Okoro, Elvis; Sundaresan, Alamelu

Changes in human foetal osteoblasts exposed to the random positioning machine and bone construct tissue engineering
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 20.2019, 6, Art.-Nr. 1357, insges. 26 S.

Begutachteter Zeitschriftenartikel

Krüger, Marcus; Kopp, Sascha; Wehland, Markus; Bauer, Johann; Baatout, Sarah; Moreels, Marjan; Egli, Marcel; Corydon, Thomas J.; Infanger, Manfred; Grimm, Daniela Gabriele

Growing blood vessels in space - preparation studies of the SPHEROIDS project using related ground-based studies
In: Acta astronautica - Amsterdam [u.a.]: Elsevier Science, Bd. 159 (2019), S. 267-272

Begutachteter Zeitschriftenartikel

Krüger, Marcus; Pietsch, Jessica; Bauer, Johann; Kopp, Sascha; Carvalho, Daniel T. O.; Baatout, Sarah; Moreels, Marjan; Melnik, Daniela; Wehland, Markus; Egli, Marcel; Sahana, Jayashree; Kobberø, Sara Dam; Corydon, Thomas J.; Nebuloni, Stefano; Gass, Samuel; Evert, Matthias; Infanger, Manfred; Grimm, Daniela Gabriele

Growth of endothelial cells in space and in simulated microgravity - a comparison on the secretory level
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 52 (2019), 5, S. 1039-1060

Begutachteter Zeitschriftenartikel

Olawi, Nasima; Krüger, Marcus; Grimm, Daniela Gabriele; Infanger, Manfred; Wehland, Markus

Nebivolol in the treatment of arterial hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 125 (2019), 3, S. 189-201

Begutachteter Zeitschriftenartikel

Krüger, Marcus; Melnik, Daniela; Kopp, Sascha; Buken, Christoph; Sahana, Jayashree; Bauer, Johann; Wehland, Markus; Hemmersbach, Ruth; Corydon, Thomas J.; Infanger, Manfred; Grimm, Daniela Gabriele

Fighting thyroid cancer with microgravity research
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 20.2019, 10, Art.-Nr. 2553, insges. 21 S.

Begutachteter Zeitschriftenartikel

Toxvig, Anne Kathrine; Wehland, Markus; Grimm, Daniela Gabriele; Infanger, Manfred; Krüger, Marcus

A focus on riociguat in the treatment of pulmonary arterial hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 125 (2019), 3, S. 202-214

Begutachteter Zeitschriftenartikel

Nassef, Mohamed Zakaria; Kopp, Sascha; Wehland, Markus; Melnik, Daniela; Sahana, Jayashree; Krüger, Marcus; Corydon, Thomas J.; Oltmann, Hergen; Schmitz, Burkhard; Schütte, Andreas; Bauer, Thomas J.; Infanger, Manfred; Grimm, Daniela Gabriele

Real microgravity influences the cytoskeleton and focal adhesions in human breast cancer cells
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 20.2019, 13, Art.-Nr. 3156, insges. 25 S.

Begutachteter Zeitschriftenartikel

Khalaf, David; Krüger, Marcus; Wehland, Markus; Infanger, Manfred; Grimm, Daniela Gabriele

The effects of oral L-arginine and L-citrulline supplementation on blood pressure
In: Nutrients - Basel: MDPI, 2009, Bd. 11.2019, 7, Art.-Nr. 1679, insges. 14 S.

Begutachteter Zeitschriftenartikel

Buken, Christoph; Sahana, Jayashree; Corydon, Thomas J.; Melnik, Daniela; Bauer, Johann; Wehland, Markus; Krüger, Marcus; Balk, Silke; Abuagela, Nauras; Infanger, Manfred; Grimm, Daniela Gabriele

Morphological and molecular changes in juvenile normal human fibroblasts exposed to simulated microgravity
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 9.2019, Art.-Nr. 11882, insges. 22 S.

Begutachteter Zeitschriftenartikel

Møller, Nanna Bæk; Budolfsen, Cecilie; Grimm, Daniela Gabriele; Krüger, Marcus; Infanger, Manfred; Wehland, Markus; Magnusson, Nils E.

Drug-induced hypertension caused by multikinase inhibitors (sorafenib, sunitinib, lenvatinib and axitinib) in renal cell carcinoma treatment
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd.20.2019, 19, Art.-Nr. 4712, insges. 23 Seiten

Begutachteter Zeitschriftenartikel

Deutch, Mikkel R.; Grimm, Daniela; Wehland, Markus; Infanger, Manfred; Krüger, Marcus

Bioactive candy - effects of licorice on the cardiovascular system
In: Foods - Basel: MDPI, 2012, Bd.8.2019, 10, Art.-Nr. 495, insges. 20 Seiten

Begutachteter Zeitschriftenartikel

Lützenberg, Ronald; Wehland, Markus; Solano, Kendrick; Nassef, Mohamed Z.; Buken, Christoph; Melnik, Daniela; Bauer, Johann; Kopp, Sascha; Krüger, Marcus; Riwaldt, Stefan; Hemmersbach, Ruth; Schulz, Herbert; Infanger, Manfred; Grimm, Daniela

Beneficial effects of low frequency vibration on human chondrocytes in vitro
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, Bd. 53 (2019), Heft 4, S. 623-637

Begutachteter Zeitschriftenartikel

Krüger, Julia; Richter, Peter; Stoltze, Julia; Strauch, Sebastian M.; Krüger, Marcus; Daiker, Viktor; Prasad, Binod; Sonnewald, Sophia; Reid, Stephen; Lebert, Michael

Changes of gene expression in Euglena gracilis obtained during the 29th DLR parabolic flight campaign
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd.9.2019, Art.-Nr. 14260, insges. 12 Seiten

Begutachteter Zeitschriftenartikel

Richter, Peter; Krüger, Marcus; Prasad, Binod; Gastiger, Susanne; Bodenschatz, Mona; Wieder, Florian; Burkovski, Andreas; Geißdörfer, Walter; Lebert, Michael; Strauch, Sebastian M.

Using colistin as a Trojan horse - inactivation of Gram-negative bacteria with chlorophyllin
In: Antibiotics - Basel: MDPI, 2012, Bd.8.2019, 4, Art.-Nr. 158, insges. 23 Seiten

Begutachteter Zeitschriftenartikel

Bauer, Thomas J.; Gombocz, Erich; Krüger, Marcus; Sahana, Jayashree; Corydon, Thomas J.; Bauer, Johann; Infanger, Manfred; Grimm, Daniela

Augmenting cancer cell proteomics with cellular images - a semantic approach to understand focal adhesion
In: Journal of biomedical informatics - San Diego, Calif.: Academic Press, Bd. 100.2019, Art.-Nr. 103320

2018

Begutachteter Zeitschriftenartikel

Sahana, Jayashree; Nassef, Mohamed Zakaria; Wehland, Markus; Kopp, Sascha; Krüger, Marcus; Corydon, Thomas J.; Infanger, Manfred; Bauer, Johann; Grimm, Daniela Gabriele

Decreased E-cadherin in MCF7 human breast cancer cells forming multicellular spheroids exposed to simulated microgravity
In: Proteomics - Weinheim: Wiley VCH, Bd. 18.2018, 13, Art.-Nr. e1800015

Begutachteter Zeitschriftenartikel

Kopp, Sascha; Krüger, Marcus; Bauer, Johann; Wehland, Markus; Corydon, Thomas J.; Sahana, Jayashree; Nassef, Mohamed Zakaria; Melnik, Daniela; Bauer, Thomas J.; Schulz, Herbert; Schütte, Andreas; Schmitz, Burkhard; Oltmann, Hergen; Feldmann, Stefan; Infanger, Manfred; Grimm, Daniela Gabriele

Microgravity affects thyroid cancer cells during the TEXUS-53 mission stronger than hypergravity
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 19.2018, 12, Art.-Nr. 4001, insges. 20 S.

Begutachteter Zeitschriftenartikel

Lützenberg, Ronald; Solano, Kendrick; Buken, Christoph; Sahana, Jayashree; Riwaldt, Stefan; Kopp, Sascha; Krüger, Marcus; Schulz, Herbert; Saar, Kathrin; Hübner, Norbert; Hemmersbach, Ruth; Bauer, Johann; Infanger, Manfred; Grimm, Daniela Gabriele; Wehland, Markus

Pathway analysis hints towards beneficial effects of long-term vibration on human chondrocytes
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 47 (2018), 4, S. 1729-1741

Begutachteter Zeitschriftenartikel

Kopp, Sascha; Krüger, Marcus; Feldmann, Stefan; Oltmann, Hergen; Schütte, Andreas; Schmitz, Burkhard; Bauer, Johann; Schulz, Herbert; Saar, Kathrin; Hübner, Norbert; Wehland, Markus; Nassef, Mohamed Zakaria; Melnik, Daniela; Meltendorf, Stefan; Infanger, Manfred; Grimm, Daniela

Thyroid cancer cells in space during the TEXUS-53 sounding rocket mission - the THYROID project
In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature - Bd. 8.2018, Art.-Nr. 10355, insges. 13 S.

Begutachteter Zeitschriftenartikel

Nielsen, Peter Munch; Grimm, Daniela Gabriele; Wehland, Markus; Simonsen, Ulf; Krüger, Marcus

The combination of valsartan and sacubitril in the treatment of hypertension and heart failure - an update
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 122 (2018), 1, S. 9-18

Begutachteter Zeitschriftenartikel

Legarth, Christian; Grimm, Daniela Gabriele; Wehland, Markus; Bauer, Johann; Krüger, Marcus

The impact of vitamin D in the treatment of essential hypertension
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 19.2018, 2, Art.-Nr. 455, insges. 14 S.

Begutachteter Zeitschriftenartikel

Dittrich, Anita; Grimm, Daniela; Sahana, Jayashree; Bauer, Johann; Krüger, Marcus; Infanger, Manfred; Magnusson, Nils E.

Key proteins involved in spheroid formation and angiogenesis in endothelial cells after long-term exposure to simulated microgravity
In: Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry and pharmacology - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 45 (2018), 2, S. 429-445

Begutachteter Zeitschriftenartikel

Pedersen, Jonas; Hedegaard, Elise R.; Simonsen, Ulf; Krüger, Marcus; Infanger, Manfred; Grimm, Daniela

Current and future treatments for persistent pulmonary hypertension in the newborn
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, 2004, Bd. 123 (2018), 4, S. 392-406

Begutachteter Zeitschriftenartikel

Grimm, Daniela Gabriele; Egli, Marcel; Krüger, Marcus; Riwaldt, Stefan; Corydon, Thomas J.; Kopp, Sascha; Wehland, Markus; Wise, Petra; Infanger, Manfred; Mann, Vivek; Sundaresan, Alamelu

Tissue engineering under microgravity conditions - use of stem cells and specialized cells
In: Stem Cells and Development - Larchmont, NY: Liebert, Bd. 27 (2018), 12, S. 787-804

Begutachteter Zeitschriftenartikel

Milling, Rikke Vilsbøll; Grimm, Daniela Gabriele; Krüger, Marcus; Grosse, Jirka; Kopp, Sascha; Bauer, Johann; Infanger, Manfred; Wehland, Markus

Pazopanib, cabozantinib, and vandetanib in the treatment of progressive medullary thyroid cancer with a special focus on the adverse effects on hypertension
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 19.2018, 10, Art.-Nr. 3258, insges. 15 S.

Begutachteter Zeitschriftenartikel

Bedan, Martin; Grimm, Daniela Gabriele; Wehland, Markus; Simonsen, Ulf; Infanger, Manfred; Krüger, Marcus

A focus on macitentan in the treatment of pulmonary arterial hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 123 (2018), 2, S. 103-113

Artikel in Kongressband

Wehland, Markus; Lützenberg, Ronald; Solano, Kendrick; Buken, Christoph; Riwaldt, Stefan; Kopp, Sascha; Krüger, Marcus; Schulz, Herbert; Hemmersbach, Ruth; Bauer, Johann; Infanger, Manfred; Grimm, Daniela

The effects of long-term vibration on human chondrocytes
In: Involving everyone / International Astronautical Congress , 2018 - Red Hook, NY : Curran Associates, Inc., Artikel IAC-18,A2,7,11,x46111

2017

Buchbeitrag

Krüger, Markus; Bauer, Johann; Grimm, Daniela

Cancer research in space
In: Biotechnology in Space - Cham: Springer, 2017 . - 2017, S. 87-106

Begutachteter Zeitschriftenartikel

Warnke, Elisabeth; Pietsch, Jessica; Kopp, Sascha; Bauer, Johann; Sahana, Jayashree; Wehland, Markus; Krüger, Marcus; Hemmersbach, Ruth; Infanger, Manfred; Lützenberg, Ronald; Grimm, Daniela

Cytokine release and focal adhesion proteins in normal thyroid cells cultured on the random positioning machine
In: Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry and pharmacology - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 43.2017, 1, S. 257-270

Begutachteter Zeitschriftenartikel

Albi, Elisabetta; Krüger, Marcus; Hemmersbach, Ruth; Lazzarini, Andrea; Cataldi, Samuela; Codini, Michela; Beccari, Tommaso; Ambesi Impiombato, Francesco; Curcio, Francesco

Impact of gravity on thyroid cells
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 18.2017, 5, Art.-Nr. 972, insges. 14 S.

Begutachteter Zeitschriftenartikel

Hjermitslev, Marie; Grimm, Daniela G.; Wehland, Markus; Simonsen, Ulf; Krüger, Marcus

Azilsartan medoxomil, an angiotensin II receptor antagonist for the treatment of hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, 2004, Bd. 121.2017, 4, S. 225-233

Begutachteter Zeitschriftenartikel

Bendtsen, Mathias Alrø Fichtner; Grimm, Daniela; Bauer, Johann; Wehland, Markus; Wise, Petra; Magnusson, Nils E.; Infanger, Manfred; Krüger, Marcus

Hypertension caused by lenvatinib and everolimus in the treatment of metastatic renal cell carcinoma
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 18.2017, 8, Art.-Nr. 1736, insges. 12 S.

Begutachteter Zeitschriftenartikel

Sørensen, Louise Marqvard; Wehland, Markus; Krüger, Marcus; Simonsen, Ulf; Nassef, Mohamed Zakaria; Infanger, Manfred; Grimm, Daniela

A special focus on selexipag - treatment of pulmonary arterial hypertension
In: Current pharmaceutical design: dispatches from the front line of drug design - Hilversum: Bentham Science Publ., 2000, Bd. 23.2017, 34, S. 5191-5199

Begutachteter Zeitschriftenartikel

Riwaldt, Stefan; Monici, Monica; Petersen, Asbjørn Graver; Jensen, Uffe Birk; Evert, Katja; Pantalone, Desiré; Utpatel, Kirsten; Evert, Matthias; Wehland, Markus; Krüger, Marcus; Kopp, Sascha; Frandsen, Sofie; Corydon, Thomas; Sahana, Jayashree; Bauer, Johann; Lützenberg, Ronald; Infanger, Manfred; Grimm, Daniela

Preparation of A spaceflight - apoptosis search in sutured wound healing models
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 18.2017, 12, Art.-Nr. 2604, insges. 22 S.

2016

Begutachteter Zeitschriftenartikel

Strauch, Sebastian M.; Richter, Peter R.; Haag, Ferdinand W.M.; Krüger, Marcus; Krüger, Julia; Azizullah, Azizullah; Breiter, Roman; Lebert, Michael

Delayed fluorescence, steady state fluorescence, photosystem II quantum yield as endpoints for toxicity evaluation of Cu2+ and Ag+
In: Environmental and Experimental Botany, 2016, S. 174-180, ISSN 00988472, 10.1016/j.envexpbot.2016.06.005

2010

Begutachteter Zeitschriftenartikel

Usai, Igor; Krueger, Marcus; Einsiedel, Jürgen; Hillen, Wolfgang; Gmeiner, Peter

Click-Chemistry-Derived Tetracycline-Amino Acid Conjugates Exhibiting Exceptional Potency and Exclusive Recognition of the Reverse Tet Repressor
In: ChemBioChem, 2010, S. 703-712, ISSN 14394227, 10.1002/cbic.200900710

2007

Begutachteter Zeitschriftenartikel

Krueger, Marcus; Scholz, Oliver; Wisshak, Stefanie; Hillen, Wolfgang

Engineered Tet repressors with recognition specificity for the tetO-4C5G operator variant
In: Gene, 2007, S. 93-100, ISSN 03781119, 10.1016/j.gene.2007.09.002

Projekte

Abgeschlossene Projekte

Einfluss der Bindung an Albumin auf die zellbiologische und molekulare Wirkungsweise von Curcumin bei benignen und malignen humanen Zellen
Laufzeit: 01.07.2021 bis 31.12.2023

Nachdem gezeigt wurde, dass Albumin-gebundenes Curcumin/HSA (wie auch reines Curcumin) eine Anti-Tumor-Wirkung in vitro besitzt, möchten wir die zellbiologischen und molekularen Wirkungsweisen von Curcumin und Curcumin/HSA auf menschliche Krebszellen am Beispiel des Mammakarzinoms ex vivo vergleichen und studieren. Hierfür befassen wir uns mit der zellbiologischen Erforschung und Evaluierung der Albumin-Carrier-Therapie mit Curcumin, durch die sich die bisher beobachteten Effekte von Curcumin/HSA auf Krebszellkulturen und Tumore in vivo besser erklären lassen. Das Projekt dient dabei nicht nur als Basis für die Weiterentwicklung klinischer Studien mit Curcumin/HSA bis hin zur Zulassung, es könnte auch weitere Ansatzpunkte für zukünftige Krebsmedikamente liefern.

Projekt im Forschungsportal ansehen

Kooperationen

Universitätsmedizin Magdeburg

  • Institut für Anatomie
    (Prof. Dr. Hermann-Josef Rothkötter, Dr. Stefan Kahlert, José Luis Cortés Sánchez)
  • Thoraxchirurgie
    (Prof. Dr. Thorsten Walles, Dr. Cornelia Wiese-Rischke)
  • Translationale Entzündungsforschung
    (Prof. Dr. Inna N. Lavrik, Fabian Wohlfromm)
  • Experminetelle Pädiatrie und Neonatologie
    (Prof. Dr. Monika Brunner-Weinzierl, Dr. Katrin Vogel)

OVGU Magdeburg

  • Core Facility Tissue Engineering
    (Prof. Dr. Heike Walles, Dr. Sascha Kopp)
  • Systembiologie
    (Prof. Dr. Fred Schaper, Dr. Anna Dittrich)

FAU Erlangen-Nürnberg

  • PD Dr. Michael Lebert, Dr. Peter Richter
  • Prof. Dr. Andreas Burkovski

Deutsches Zentrum für Luft- und Raumfahrt, Köln

  • Dr. Christian Liemersdorf

Aarhus University (DK)

  • Prof. Dr. Thomas Corydon

HSLU Luzern (CH)

  • Dr. Simon L Wüest

Institute of Molecular Bioimaging and Physiology of the Italian National Research Council (IT)

  • Dr. Marco Calvaruso

SCK-CEN Belgian Nuclear Research Centre (BE)

  •  Prof. Dr. Sarah Baatout, Dr. Bjorn Baselet

Universidade da Região de Joinville (BR)

  • Dr. Sebastian M. Strauch
Lehrveranstaltungen

Letzte Änderung: 07.07.2023 - Ansprechpartner:

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