Dr. rer. nat. Marcus Krüger
Dr. rer. nat. Marcus Krüger
AG Umweltzellbiologie
2024
Begutachteter Zeitschriftenartikel
Omics studies of tumor cells under microgravity conditions
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 25 (2024), Heft 2, Artikel 926, insges. 48 S.
Begutachteter Zeitschriftenartikel
Changes in gravitaxis and gene-expression in an Euglena gracilis culture over time
In: Biomolecules - Basel : MDPI, Bd. 14 (2024), Heft 3, Artikel 327, insges. 15 S.
2023
Begutachteter Zeitschriftenartikel
Current knowledge about the impact of microgravity on gene regulation
In: Cells - Basel : MDPI, Bd. 12 (2023), Heft 7, Artikel 1043, insges. 59 S.
Begutachteter Zeitschriftenartikel
Remove, refine, reduce - cell death in biological systems
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 24 (2023), Heft 8, Artikel 7028, insges. 5 S.
Begutachteter Zeitschriftenartikel
A dusty road for astronauts
In: Biomedicines - Basel : MDPI, Bd. 11 (2023), Heft 7, Artikel 1921, insges. 21 S.
Begutachteter Zeitschriftenartikel
Fluid and bubble flow detach adherent cancer cells to form spheroids on a random positioning machine
In: Cells - Basel : MDPI, Bd. 12 (2023), Heft 22, Artikel 2665, insges. 27 S.
Begutachteter Zeitschriftenartikel
Dexamethasone selectively inhibits detachment of metastatic thyroid cancer cells during random positioning
In: Cancers - Basel : MDPI, Bd. 15 (2023), Heft 6, Artikel 1641, insges. 25 S.
Begutachteter Zeitschriftenartikel
Tumor models and drug targeting in vitro - where are we today? : Where do we go from here?
In: Cancers - Basel : MDPI, Bd. 15 (2023), Heft 6, Artikel 1768, insges. 5 S.
2022
Begutachteter Zeitschriftenartikel
Cancer studies under space conditions - finding answers abroad
In: Biomedicines - Basel : MDPI, Bd. 10 (2022), Heft 1, Artikel 25, insges. 28 S.
Begutachteter Zeitschriftenartikel
Polyethylenimine increases antibacterial efficiency of chlorophyllin
In: Antibiotics - Basel: MDPI, 2012, Bd. 11 (2022), 10, insges. 15 S.
Begutachteter Zeitschriftenartikel
Latest knowledge about changes in the proteome in microgravity
In: Expert review of proteomics - Abingdon : Taylor & Francis Group, Bd. 19 (2022), Heft 1, S. 43-59
Begutachteter Zeitschriftenartikel
Three-dimensional growth of prostate cancer cells exposed to simulated microgravity
In: Frontiers in cell and developmental biology - Lausanne : Frontiers Media, Bd. 10 (2022), Artikel 841017, insges. 21 S.
Begutachteter Zeitschriftenartikel
The fight against cancer by microgravity - the multicellular spheroid as a metastasis model
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 23 (2022), Heft 6, Artikel 3073, insges. 45 S.
Begutachteter Zeitschriftenartikel
To die or not to die - cell death in biology and disease
In: International journal of molecular sciences - Basel : Molecular Diversity Preservation International, Bd. 23 (2022), Heft 12, Artikel 6734, insges. 3 S.
2021
Begutachteter Zeitschriftenartikel
Alterations of growth and focal adhesion molecules in human breast cancer cells exposed to the random positioning machine
In: Frontiers in cell and developmental biology - Lausanne: Frontiers Media, 2013, Bd. 9 (2021), insges. 17 S.
Begutachteter Zeitschriftenartikel
Changes in exosome release in thyroid cancer cells after prolonged exposure to real microgravity in space
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 4, insges. 19 S.
Begutachteter Zeitschriftenartikel
Natural products in modern biology - ancient wisdom for todays challenges
In: Biology - Basel : MDPI, Bd. 10 (2021), Heft 5, Artikel 369, insges. 3 S.
Begutachteter Zeitschriftenartikel
SARS-CoV-2 and hypertension
In: Physiological reports - [S.l.]: Wiley, 2013, Bd. 9 (2021), insges. 14 S.
Begutachteter Zeitschriftenartikel
Role of apoptosis in wound healing and apoptosis alterations in microgravity
In: Frontiers in Bioengineering and Biotechnology - Lausanne: Frontiers Media, 2013, Bd. 9 (2021), insges. 22 S.
Begutachteter Zeitschriftenartikel
Changes in exosomal miRNA composition in thyroid cancer cells after prolonged exposure to real microgravity in space
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 23, insges. 24 S.
Begutachteter Zeitschriftenartikel
Kinase-inhibitors in iodine-refractory differentiated thyroid cancer - focus on occurrence, mechanisms, and management of treatment-related hypertension
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 22, insges. 23 S.
Begutachteter Zeitschriftenartikel
The CellBox-2 Mission to the International Space Station - thyroid cancer cells in space
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 22 (2021), 16, insges. 21 S.
2020
Begutachteter Zeitschriftenartikel
Multikinase inhibitor treatment in thyroid cancer
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 1, Art.-Nr. 10, insges. 19 Seiten
Begutachteter Zeitschriftenartikel
Potential beneficial effects of vitamin D in coronary artery disease
In: Nutrients - Basel: MDPI, 2009, Vol.12.2020, 1, Art.-Nr. 99, insges. 22 Seiten
Begutachteter Zeitschriftenartikel
The role of SOX family members in solid tumours and metastasis
In: Seminars in cancer biology - London: Academic Press, 1995, Bd. 67 (2020), 1, S. 122-153, 2019
Begutachteter Zeitschriftenartikel
Influence of microgravity on apoptosis in cells, tissues, and other systems in vivo and in vitro
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 24, 9373, insgesamt 32 Seiten
Begutachteter Zeitschriftenartikel
Ethyl pyruvate reduces systemic leukocyte activation via caspase-1 and NF-[kappa]B after blunt chest trauma and haemorrhagic shock
In: Frontiers in medicine - Lausanne: Frontiers Media, 2014, Bd. 7.2020, Art.-Nr. 562904, insgesamt 11 Seiten
Begutachteter Zeitschriftenartikel
Breast cancer cells in microgravity - new aspects for cancer research
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 19, Art.-Nr. 7345, insges. 22 Seiten
Begutachteter Zeitschriftenartikel
Science between bioreactors and space research - response to comments by Joseph J. Bevelacqua et al. on Dexamethasone Inhibits Spheroid Formation of Thyroid Cancer Cells Exposed to Simulated Microgravity
In: Cells - Basel: MDPI, 2012, Vol. 9.2020, 8, Art.-Nr. 1763, insges. 3 Seiten
Begutachteter Zeitschriftenartikel
Exploration of space to achieve scientific breakthroughs
In: Biotechnology advances : research reviews and patent abstracts - Amsterdam : Elsevier Science Publ. - Vol. 43.2020, Art.-Nr. 107572, insges. 33 Seiten
Begutachteter Zeitschriftenartikel
The effects of microgravity on differentiation and cell growth in stem cells and cancer stem cells
In: Stem cells translational medicine - Durham: AlphaMed Press, 2012, Bd. 9 (2020), 8, S. 882-894
Begutachteter Zeitschriftenartikel
Endothelin receptor antagonists - status quo and future perspectives for targeted therapy
In: Journal of Clinical Medicine - Basel: MDPI, 2012, Bd. 9.2020, 3, Art.-Nr. 824, insges. 29 Seiten
Begutachteter Zeitschriftenartikel
The prostacyclin analogue treprostinil in the treatment of pulmonary arterial hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 126 (2020), 1, S. 32-42
Begutachteter Zeitschriftenartikel
An evaluation of the fixed-dose combination sacubitril/valsartan for the treatment of arterial hypertension
In: Expert opinion on pharmacotherapy - Abingdon, Oxon: Routledge, Taylor & Francis, Bd. 21 (2020), 10, S. 1133-1143
Begutachteter Zeitschriftenartikel
Simulated microgravity influences VEGF, MAPK, and PAM signaling in prostate cancer cells
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Vol. 21.2020, 4, Art.-Nr. 1263, insges. 26 Seiten
Begutachteter Zeitschriftenartikel
Dexamethasone inhibits spheroid formation of thyroid cancer cells exposed to simulated microgravity
In: Cells - Basel: MDPI, 2012, Vol. 9.2020, 2, Art.-Nr. 367, insges. 25 Seiten
Begutachteter Zeitschriftenartikel
The vasoactive mas receptor in essential hypertension
In: Journal of Clinical Medicine - Basel: MDPI, 2012, Bd. 9.2020, 1, Art.-Nr. 267, insges. 12 Seiten
2019
Abstract
Microgravity-based modulation of VEGF expression in human thyroid carcinoma cells
In: Frontiers in physiology - Lausanne: Frontiers Research Foundation, 2007, Bd. 10.2019, Abstract 2, insges. 4 S.
Abstract
Growing tissues in space
In: Frontiers in physiology - Lausanne: Frontiers Research Foundation, 2007, Bd. 10.2019, Abstract 14, insges. 3 S.
Abstract
Alterations of the cytoskeleton in breast cancer cells during microgravity visualised by FLUMIAS live-cell imaging
In: Frontiers in physiology - Lausanne: Frontiers Research Foundation, 2007, Bd. 10.2019, Abstract 8, insges. 3 S.
Begutachteter Zeitschriftenartikel
Using colistin as a Trojan horse - inactivation of Gram-negative bacteria with chlorophyllin
In: Antibiotics - Basel: MDPI, 2012, Bd.8.2019, 4, Art.-Nr. 158, insges. 23 Seiten
Begutachteter Zeitschriftenartikel
Current knowledge about the impact of microgravity on the proteome
In: Expert review of proteomics - Abingdon: Taylor & Francis Group, Bd. 16 (2019), 1, S. 5-16
Begutachteter Zeitschriftenartikel
Tyrosine kinase inhibitor-induced hypertension - role of hypertension as a biomarker in cancer treatment
In: Current vascular pharmacology - Hilversum [u.a.]: Bentham Science Publ., Bd. 17 (2019), 6, S. 618-634
Begutachteter Zeitschriftenartikel
What an Escherichia coli mutant can teach us about the antibacterial effect of chlorophyllin
In: Microorganisms - Basel: MDPI, Bd. 7.2019, 2, Art.-Nr. 59, insges. 23 S.
Begutachteter Zeitschriftenartikel
Changes in human foetal osteoblasts exposed to the random positioning machine and bone construct tissue engineering
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 20.2019, 6, Art.-Nr. 1357, insges. 26 S.
Begutachteter Zeitschriftenartikel
Growing blood vessels in space - preparation studies of the SPHEROIDS project using related ground-based studies
In: Acta astronautica - Amsterdam [u.a.]: Elsevier Science, Bd. 159 (2019), S. 267-272
Begutachteter Zeitschriftenartikel
Growth of endothelial cells in space and in simulated microgravity - a comparison on the secretory level
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 52 (2019), 5, S. 1039-1060
Begutachteter Zeitschriftenartikel
Nebivolol in the treatment of arterial hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 125 (2019), 3, S. 189-201
Begutachteter Zeitschriftenartikel
Fighting thyroid cancer with microgravity research
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 20.2019, 10, Art.-Nr. 2553, insges. 21 S.
Begutachteter Zeitschriftenartikel
A focus on riociguat in the treatment of pulmonary arterial hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 125 (2019), 3, S. 202-214
Begutachteter Zeitschriftenartikel
Real microgravity influences the cytoskeleton and focal adhesions in human breast cancer cells
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 20.2019, 13, Art.-Nr. 3156, insges. 25 S.
Begutachteter Zeitschriftenartikel
The effects of oral L-arginine and L-citrulline supplementation on blood pressure
In: Nutrients - Basel: MDPI, 2009, Bd. 11.2019, 7, Art.-Nr. 1679, insges. 14 S.
Begutachteter Zeitschriftenartikel
Morphological and molecular changes in juvenile normal human fibroblasts exposed to simulated microgravity
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd. 9.2019, Art.-Nr. 11882, insges. 22 S.
Begutachteter Zeitschriftenartikel
Drug-induced hypertension caused by multikinase inhibitors (sorafenib, sunitinib, lenvatinib and axitinib) in renal cell carcinoma treatment
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd.20.2019, 19, Art.-Nr. 4712, insges. 23 Seiten
Begutachteter Zeitschriftenartikel
Bioactive candy - effects of licorice on the cardiovascular system
In: Foods - Basel: MDPI, 2012, Bd.8.2019, 10, Art.-Nr. 495, insges. 20 Seiten
Begutachteter Zeitschriftenartikel
Beneficial effects of low frequency vibration on human chondrocytes in vitro
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, Bd. 53 (2019), Heft 4, S. 623-637
Begutachteter Zeitschriftenartikel
Changes of gene expression in Euglena gracilis obtained during the 29th DLR parabolic flight campaign
In: Scientific reports - [London]: Macmillan Publishers Limited, part of Springer Nature, 2011, Bd.9.2019, Art.-Nr. 14260, insges. 12 Seiten
Begutachteter Zeitschriftenartikel
Augmenting cancer cell proteomics with cellular images - a semantic approach to understand focal adhesion
In: Journal of biomedical informatics - San Diego, Calif.: Academic Press, Bd. 100.2019, Art.-Nr. 103320
Begutachteter Zeitschriftenartikel
Short-term microgravity influences cell adhesion in human breast cancer cells
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 20.2019, 22, Art.-Nr. 5730, insges. 27 Seiten
2018
Begutachteter Zeitschriftenartikel
Thyroid cancer cells in space during the TEXUS-53 sounding rocket mission - the THYROID project
In: Scientific reports - [London] : Macmillan Publishers Limited, part of Springer Nature - Bd. 8.2018, Art.-Nr. 10355, insges. 13 S.
Begutachteter Zeitschriftenartikel
Microgravity affects thyroid cancer cells during the TEXUS-53 mission stronger than hypergravity
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 19.2018, 12, Art.-Nr. 4001, insges. 20 S.
Begutachteter Zeitschriftenartikel
Pathway analysis hints towards beneficial effects of long-term vibration on human chondrocytes
In: Cellular physiology and biochemistry - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 47 (2018), 4, S. 1729-1741
Begutachteter Zeitschriftenartikel
Decreased E-cadherin in MCF7 human breast cancer cells forming multicellular spheroids exposed to simulated microgravity
In: Proteomics - Weinheim: Wiley VCH, Bd. 18.2018, 13, Art.-Nr. e1800015
Begutachteter Zeitschriftenartikel
The combination of valsartan and sacubitril in the treatment of hypertension and heart failure - an update
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 122 (2018), 1, S. 9-18
Begutachteter Zeitschriftenartikel
The impact of vitamin D in the treatment of essential hypertension
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 19.2018, 2, Art.-Nr. 455, insges. 14 S.
Begutachteter Zeitschriftenartikel
Key proteins involved in spheroid formation and angiogenesis in endothelial cells after long-term exposure to simulated microgravity
In: Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry and pharmacology - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 45 (2018), 2, S. 429-445
Begutachteter Zeitschriftenartikel
Current and future treatments for persistent pulmonary hypertension in the newborn
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, 2004, Bd. 123 (2018), 4, S. 392-406
Begutachteter Zeitschriftenartikel
Tissue engineering under microgravity conditions - use of stem cells and specialized cells
In: Stem Cells and Development - Larchmont, NY: Liebert, Bd. 27 (2018), 12, S. 787-804
Begutachteter Zeitschriftenartikel
Pazopanib, cabozantinib, and vandetanib in the treatment of progressive medullary thyroid cancer with a special focus on the adverse effects on hypertension
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 19.2018, 10, Art.-Nr. 3258, insges. 15 S.
Begutachteter Zeitschriftenartikel
A focus on macitentan in the treatment of pulmonary arterial hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, Bd. 123 (2018), 2, S. 103-113
Artikel in Kongressband
The effects of long-term vibration on human chondrocytes
In: Involving everyone / International Astronautical Congress , 2018 - Red Hook, NY : Curran Associates, Inc., Artikel IAC-18,A2,7,11,x46111
2017
Buchbeitrag
Cancer research in space
In: Biotechnology in Space - Cham: Springer, 2017 . - 2017, S. 87-106
Begutachteter Zeitschriftenartikel
Cytokine release and focal adhesion proteins in normal thyroid cells cultured on the random positioning machine
In: Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry and pharmacology - Düsseldorf: Cell Physiol Biochem Press GmbH & Co KG, 1991, Bd. 43.2017, 1, S. 257-270
Begutachteter Zeitschriftenartikel
Impact of gravity on thyroid cells
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 18.2017, 5, Art.-Nr. 972, insges. 14 S.
Begutachteter Zeitschriftenartikel
Azilsartan medoxomil, an angiotensin II receptor antagonist for the treatment of hypertension
In: Basic & clinical pharmacology & toxicology - Oxford: Wiley-Blackwell, 2004, Bd. 121.2017, 4, S. 225-233
Begutachteter Zeitschriftenartikel
Hypertension caused by lenvatinib and everolimus in the treatment of metastatic renal cell carcinoma
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 18.2017, 8, Art.-Nr. 1736, insges. 12 S.
Begutachteter Zeitschriftenartikel
A special focus on selexipag - treatment of pulmonary arterial hypertension
In: Current pharmaceutical design: dispatches from the front line of drug design - Hilversum: Bentham Science Publ., 2000, Bd. 23.2017, 34, S. 5191-5199
Begutachteter Zeitschriftenartikel
Preparation of A spaceflight - apoptosis search in sutured wound healing models
In: International journal of molecular sciences - Basel: Molecular Diversity Preservation International, 2000, Bd. 18.2017, 12, Art.-Nr. 2604, insges. 22 S.
2016
Begutachteter Zeitschriftenartikel
Delayed fluorescence, steady state fluorescence, photosystem II quantum yield as endpoints for toxicity evaluation of Cu2+ and Ag+
In: Environmental and Experimental Botany, 2016, S. 174-180, ISSN 00988472, 10.1016/j.envexpbot.2016.06.005
2010
Begutachteter Zeitschriftenartikel
Click-Chemistry-Derived Tetracycline-Amino Acid Conjugates Exhibiting Exceptional Potency and Exclusive Recognition of the Reverse Tet Repressor
In: ChemBioChem, 2010, S. 703-712, ISSN 14394227, 10.1002/cbic.200900710
2007
Begutachteter Zeitschriftenartikel
Engineered Tet repressors with recognition specificity for the tetO-4C5G operator variant
In: Gene, 2007, S. 93-100, ISSN 03781119, 10.1016/j.gene.2007.09.002
Abgeschlossene Projekte
Einfluss der Bindung an Albumin auf die zellbiologische und molekulare Wirkungsweise von Curcumin bei benignen und malignen humanen Zellen
Laufzeit: 01.07.2021 bis 31.12.2023
Nachdem gezeigt wurde, dass Albumin-gebundenes Curcumin/HSA (wie auch reines Curcumin) eine Anti-Tumor-Wirkung in vitro besitzt, möchten wir die zellbiologischen und molekularen Wirkungsweisen von Curcumin und Curcumin/HSA auf menschliche Krebszellen am Beispiel des Mammakarzinoms ex vivo vergleichen und studieren. Hierfür befassen wir uns mit der zellbiologischen Erforschung und Evaluierung der Albumin-Carrier-Therapie mit Curcumin, durch die sich die bisher beobachteten Effekte von Curcumin/HSA auf Krebszellkulturen und Tumore in vivo besser erklären lassen. Das Projekt dient dabei nicht nur als Basis für die Weiterentwicklung klinischer Studien mit Curcumin/HSA bis hin zur Zulassung, es könnte auch weitere Ansatzpunkte für zukünftige Krebsmedikamente liefern.
Universitätsmedizin Magdeburg
- Institut für Anatomie
(Prof. Dr. Hermann-Josef Rothkötter, Dr. Stefan Kahlert, José Luis Cortés Sánchez) - Thoraxchirurgie
(Prof. Dr. Thorsten Walles, Dr. Cornelia Wiese-Rischke) - Translationale Entzündungsforschung
(Prof. Dr. Inna N. Lavrik, Fabian Wohlfromm) - Experminetelle Pädiatrie und Neonatologie
(Prof. Dr. Monika Brunner-Weinzierl, Dr. Katrin Vogel)
OVGU Magdeburg
- Core Facility Tissue Engineering
(Prof. Dr. Heike Walles, Dr. Sascha Kopp) - Systembiologie
(Prof. Dr. Fred Schaper, Dr. Anna Dittrich)
FAU Erlangen-Nürnberg
- PD Dr. Michael Lebert, Dr. Peter Richter
- Prof. Dr. Andreas Burkovski
Deutsches Zentrum für Luft- und Raumfahrt, Köln
- Dr. Christian Liemersdorf
Aarhus University (DK)
- Prof. Dr. Thomas Corydon
HSLU Luzern (CH)
- Dr. Simon L Wüest
Institute of Molecular Bioimaging and Physiology of the Italian National Research Council (IT)
- Dr. Marco Calvaruso
SCK-CEN Belgian Nuclear Research Centre (BE)
- Prof. Dr. Sarah Baatout, Dr. Bjorn Baselet
Universidade da Região de Joinville (BR)
- Dr. Sebastian M. Strauch
- Biochemistry /Biomedicine ( Link zur LV im LSF )
- Biochemistry / Biomedicine - Seminar ( Link zur LV im LSF )
- Forschung in Mikrogravitation: Grundlagen, Methoden, Experimente ( Link zur LV im LSF )
- Zellbiologische Übungen in Mikrogravitation ( Link zur LV im LSF )